Mogrify Solidifies IP Position Surrounding Core Technology and Expands Platform Algorithm to Enhance Cell Conversion | BioSpace

Dec. 17, 2020 09:45 UTC

CAMBRIDGE, England–(BUSINESS WIRE)– Mogrify Limited (Mogrify®), a UK company aiming to transform the development of ex vivo cell therapies and pioneer the field of in vivo reprogramming therapies, today announced it had secured the assignment of the foundational intellectual property (IP) underpinning its core direct cell conversion technology (MOGRIFY® V1) and extended the method to allow for the inclusion of new sources of data and more accurate transcription factor predictions (MOGRIFY V2). The expansion of rights has allowed the Company to bring the latest version of the technology in-house.

The MOGRIFY platform utilizes a systematic big-data approach (Rackham et al., Nature Genetics, 2016) developed over a 10-year period via a multi-national research collaboration. By deploying next-generation sequencing and gene regulatory data, the platform enables the prediction of the transcription factors (or small…

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